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相关概念视频

Sampling Methods: Sample Types01:18

Sampling Methods: Sample Types

183
Sampling materials are classified into three main types: solid, liquid, and gas.
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
183
Systematic Error: Methodological and Sampling Errors01:15

Systematic Error: Methodological and Sampling Errors

1.4K
In the case of systematic errors, the sources can be identified, and the errors can be subsequently minimized by addressing these sources. According to the source, systematic errors can be divided into sampling, instrumental, methodological, and personal errors.
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...
1.4K
Glassware Calibration01:11

Glassware Calibration

195
Accurate calibration of glassware, such as volumetric flasks, pipettes, and burettes, is essential to ensure accurate measurements in the analytical laboratory. Calibration helps maintain consistency across measurements and prevents errors arising from inaccurate volumes.
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...
195
Contaminants and Errors01:16

Contaminants and Errors

85
Effective sample preparation is crucial for accurate and reliable laboratory analysis. During this process, two significant sources of error can arise: concentration bias from improper sample splitting and contamination caused by methods used to reduce particle size, such as grinding or homogenization. Identifying and minimizing these potential errors is crucial to ensuring the validity of the analysis.
Another key consideration is determining the appropriate number of samples required to...
85
Control Volume and System Representations01:16

Control Volume and System Representations

871
Two key frameworks are employed to analyze mass, energy, and momentum transfer: the control volume approach and the system approach. These frameworks offer different perspectives, depending on whether the focus is on a specific region in space (control volume approach) or a defined mass of fluid (system approach).
The control volume approach considers a stationary region in space through which fluid flows. This region is bounded by a control surface.  For instance, in the case of water...
871

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相关实验视频

Updated: Jun 8, 2025

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
07:57

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

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稳定性研究中的潜在采样错误 由于封闭系统传输装置中的死体积

Mélanie Closset1,2,3, Maire-Lise Colsoul1,3, Benoît Bihin2,4

  • 1Medical Laboratory, CHU UCL NAMUR, Yvoir, Belgium.

The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians
|November 7, 2024
PubMed
概括

封闭系统传输装置 (CSTD) 可能会在抗癌药物稳定性研究中引入偏差. Tevadaptor®装置在初始样本中高估了gemcitabine度,突出了了解CSTD技术规格的必要性.

科学领域:

  • 制药科学 制药科学
  • 药物稳定性测试 药物稳定性测试
  • 分析化学 分析化学

背景情况:

  • 封闭系统传输装置 (CSTD) 用于尽量减少医疗保健专业人员对危险药物的暴露.
  • 它们的应用在抗癌药物的稳定性研究中很常见,例如gemcitabine.
  • 研究了一种特定的CSTD,Tevadaptor®,以确定gemcitabine稳定性评估中的潜在偏差.
关键词:
抗癌药物是一种抗癌药物.封闭系统传输装置 (CSTD) 是一个关闭系统传输装置.液体色谱学 液体色谱学 液体色谱学稳定性研究研究.在 Tevadaptor® 的使用中.

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