相关实验视频

Updated: May 2, 2026

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

Published on: September 17, 2013

[利用声动力学疗法诱导的肝癌治疗中的灭]

Nisi Zhang¹, Zhifei Dai¹

¹（ 100871） Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing 100871, China.

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

|November 7, 2024

概括

声动力学疗法 (SDT) 通过诱导炎症性细胞死亡 - - 炎症性细胞死亡 - - 诱导亡,对肝癌具有前景. 这种方法使用超声波和声敏剂产生活性氧物种 (ROS),抑制瘤生长并增强免疫反应.

科学领域:

在瘤学瘤学.
生物化学生物化学
免疫学免疫学免疫学

背景情况:

肝癌仍然是癌症死亡的主要原因,治疗治疗有限.
炎症性细胞死亡途径与氧化应激相关的炎症性细胞死亡途径 Pyroptosis 呈现出一种新的治疗途径.
声动疗 (SDT) 产生细胞毒性反应性氧物种 (ROS) 用于癌症治疗,显示肝癌的潜力.

研究的目的:

审查pyroptosis在肝癌治疗中的潜力.
阐明SDT诱导的ROS生成用于癌症治疗的机制.
讨论SDT对肝癌的最新发现和前景.

主要方法:

审查现有的临床前和临床研究在肝癌中皮रोप托斯和SDT.
通过SDT对ROS生成机制的分析.
讨论SDT对瘤增殖和免疫反应的影响.

主要成果:

SDT可以诱导瘤中过度的ROS积累,超过细胞毒性值.
通过SDT介导的ROS诱导促进热,抑制瘤增殖.
通过SDT增强ROS的产生改善了抗瘤免疫反应.

结论:

SDT诱导的热是肝癌治疗的一个有前途的策略.
了解SDT的机制为临床翻译提供了基础.
需要进一步的研究来优化SDT条件,并充分阐明其对肝癌治疗的生物效应.

关键词:

免疫治疗是一种免疫疗法.肝癌是一种肝癌.热灭菌的发生.审查审查审查审查声动力学疗法声动力学疗法超声波超声波是指超声波的使用.

更多相关视频

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Published on: January 9, 2019

Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System

Sonodynamic Therapy for the Treatment of Glioblastoma Multiforme in a Mouse Model Using a Portable Benchtop Focused Ultrasound System

Published on: February 10, 2023

相关概念视频

Cancer Therapies

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.