外周止痛疗法与术后疼痛管理的全身阿片类药物对比:VATS后系统性审查的协议
Jimmy H Holm1, Mikkel Bak1, Anne C Brøchner2,3
1Department of Anaesthesia and Intensive Care, Odense University Hospital, Odense, Denmark.
Acta anaesthesiologica Scandinavica
|November 7, 2024
概括
本综述将系统性阿片类药物与视频辅助胸腔镜手术 (VATS) 后术后疼痛的外周止痛药进行比较. 它旨在确定对VATS患者最有效和最安全的疼痛管理策略.
科学领域:
- 麻醉学和疼痛管理
- 胸部外科手术 胸部外科手术
- 基于证据的医学基于证据的医学.
背景情况:
- 视频辅助胸腔镜手术 (VATS) 后的术后疼痛是一个重大的临床挑战.
- 外周止痛是当前的标准,但由于并发症风险较低,越来越多地探索区域止痛选择.
- 系统性阿片类药物与外围止痛药对VATS疼痛的比较疗效尚未得到充分证实.
研究的目的:
- 系统地审查和对系统性阿片类药物的疗效进行元分析,与外周止痛相比,用于管理VATS后的术后疼痛.
- 为了评估疼痛强度,阿片类药物消费,住院和与每种止痛方法相关的不良事件.
主要方法:
- 根据柯克兰手册和PRISMA-P指南进行系统审查和元分析.
- 在主要数据库 (MEDLINE,EMBASE,Cochrane Library) 和灰色文献中进行全面的文献搜索.
- 包括基于PICO方法的研究,独立提取数据和偏差风险评估.
主要成果:
- 系统性阿片类药物与外围止痛药对VATS手术后疼痛的比较分析.
- 数据综合将包括疼痛评分,救援阿片类药物使用,住院时间和不良事件的综合估计.
- 将进行子组和灵敏度分析,以解决研究异质性的问题.
结论:
- 这一审查将为VATS的最佳疼痛管理策略提供关键的见解.
- 结果将为临床实践提供有关VATS患者最有效和安全的止痛方法的信息.
- 该研究旨在改善术后康复和患者的治疗结果.
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