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Updated: Jun 8, 2025

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移动胆固醇抗性蛋白的活性部位的序列变异是通过域间相互作用进化地适应的

Avani Joshi1, Nishad Matange1

  • 1Department of Biology, Indian Institute of Science Education and Research, Pashan, Pune, India.

The Biochemical journal
|November 7, 2024
PubMed
概括

移动胆固醇耐药性 (MCR) 蛋白质中自然存在的变异会影响抗生素耐药性. 在MCR-1和MCR-5蛋白质结构中微妙的差异解释了为什么突变会以不同的方式影响胆固醇抗性.

关键词:
在AlphaFold建模中使用AlphaFold模型.最多的CRM是可以使用的.抗微生物耐药性 抗微生物耐药性科里斯 (Colistin) 是一个古老的城市.自然序列变化的变化.

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