在怀孕的前八十天内,母亲的营养不良会对乳牛小牛的卵巢发育产生负面影响
Adele Frau1, David Edache2, Sebastiano Sale3
1Department of Veterinary Medicine, University of Sassari, Sassari, Italy.
Biology of reproduction
|November 7, 2024
概括
乳牛在怀孕早期受到母体能量限制会损害雌牛的卵巢发育,影响卵泡数量和AMH水平. 心血管发育没有受到营养干预的影响.
科学领域:
- 生殖生物学 生殖生物学
- 发展规划是指发展规划.
- 动物科学动物科学
背景情况:
- 孕期母亲的营养影响后代的发育.
- 怀孕早期的营养限制可能会影响牲畜的生殖潜力.
- 了解发展规划的关键窗口对于畜牧业至关重要.
研究的目的:
- 调查在特定妊娠窗口期间对母体能量限制对幼母乳牛卵巢和心血管发育的影响.
- 探索母亲的瘦素和在子女发育规划中的作用.
- 为了确定孕期的关键时期,用于对生殖特征的营养编程.
主要方法:
- 在怀孕80天 (NR80) 或120天 (NR120) 之前,荷尔斯坦-弗里西亚公牛被分配到控制 (1.8M) 或营养限制 (0.6M) 的饮食中.
- 后代的卵巢发育通过淋巴体体重,毛囊数量,恢复的卵细胞和AMH度来评估.
- 用血压,心声学和尸体分析来评估心血管功能.
主要成果:
- 无论持续时间如何,母亲的能量受限,女性后代的卵巢发育受损,以减少淋巴体重量,较少的卵泡和较低的AMH为证据.
- 心血管形态和功能没有受到母亲饮食治疗的显著影响.
- 在受限小牛中观察到母体血瘦素的暂时增加,这表明在编程中可能发挥作用.
结论:
- 孕期早期母亲的能量限制严重影响了幼母乳牛的卵巢发育.
- 卵巢前期到怀孕的前2.6个月似乎对卵巢编程至关重要.
- 孕产妇的瘦素可能在调节营养限制对后代生殖发育的影响方面发挥作用.
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