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Updated: Jun 8, 2025

Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin
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Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin

Published on: January 17, 2012

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调节性T细胞的依赖progranulin的修复功能驱动骨折愈合

Ruiying Chen1, Xiaomeng Zhang1, Bin Li2,3,4,5

  • 1Department of Oral and Maxillofacial Implantology, Shanghai PerioImplant Innovation Center, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai, China.

The Journal of clinical investigation
|November 7, 2024
PubMed
概括

表达CCR8的特种Tregs迁移到骨损伤部位,促进骨干干细胞的修复. 这些Tregs分泌progranulin (PGRN),通过免疫细胞信号增强骨再生.

关键词:
骨生物学 骨生物学骨疾病是一种骨疾病.骨髓 骨髓 骨髓 骨髓 骨髓

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