象牙海岸的HIV-1和HIV-2流行病的负担
Bérenger Konan1, Carmen de Mendoza2, Christ-Hermannn Kouadio1
1Centre Médico-Social Walé, Yamoussoukro, Ivory Coast
AIDS reviews
|November 7, 2024
概括
象牙海岸的艾滋病毒大流行是一个主要的公共卫生问题,艾滋病毒-1病例的增加和大量未被诊断的感染. 扩大诊断和维持治疗对于管理艾滋病毒和共感染至关重要.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 复原病毒学 复原病毒学
背景情况:
- 类似免疫缺陷病毒 (SIV) 是人类免疫缺陷病毒 (HIV) 的前体.
- 包括科特迪瓦在内的西非国家是从灵长类动物向人类传播逆转录病毒的地区.
- 科特迪瓦有大量艾滋病毒感染者 (PLWH),其中很大一部分未被诊断出来.
研究的目的:
- 为了评估目前的艾滋病毒流行病在科特迪瓦.
- 评估该国艾滋病毒和共感染的管理.
- 确定需要改进的艾滋病毒预防,诊断和治疗策略的领域.
主要方法:
- 在2024年初进行了一项全国性的调查.
- 收集了PLWH的数量,HIV类型 (HIV-1,HIV-2),共感染和处方抗逆转录病毒治疗的数据.
- 分析了病毒抑制率和治疗中断.
主要成果:
- 总共有188,880名PLWH接受了随访,HIV-1比HIV-2更为普遍.
- 最常见的抗逆转录病毒疗法是特诺福维尔,拉米武丁和多卢特格拉维尔,达到94.3%的病毒抑制.
- 与HTLV-1和肝炎病毒的同时感染是常见的,但往往未被诊断和管理不善.
结论:
- 艾滋病毒,特别是艾滋病毒-1,仍然是象牙海岸的主要公共卫生挑战.
- 维持抗逆转录病毒治疗和改善共感染的诊断和管理至关重要.
- 需要加强战略来扩大艾滋病毒诊断,并确保持续的治疗机会.
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