对中东的抗毒疗法的评估 子毒液中毒
Inbal Kestenbom1, Gidon Test1, Or Kaplan1
1From the Division of Pediatric Emergency Medicine, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University, Beer Sheva, Israel.
Pediatric emergency care
|November 7, 2024
概括
SCORPIFAV抗毒药有效治疗儿科子中毒,导致症状迅速消失. 所有患者完全康复,过敏反应最小,支持更广泛的抗毒药可用性.
科学领域:
- 毒理学 毒理学 毒理学
- 儿科医学 儿科医学
- 免疫学 免疫学 免疫学
背景情况:
- 子中毒是该地区的一个重大健康问题.
- 常见的子包括Leiurus quinquestriatus,Androctonus australis和Buthus occitanus. 这些子通常被认为是子.
- 自2016年以来,SCORPIFAV,一种多用途的子抗毒F(ab') 2 (马),一直在使用.
研究的目的:
- 描述被普通有毒子毒害的儿童的结果.
- 评估SCORPIFAV在儿科患者中的疗效和安全性.
主要方法:
- 在2019年9月至2020年12月期间接受子中毒的儿童的回顾性图表审查.
- 纳入标准:使用SCORPIFAV抗毒剂.
- 对患有自主激发,兴奋或焦虑的患者,强制使用抗毒疗法.
主要成果:
- 在300名儿科患者中,有49人接受了SCORPIFAV.
- 四名患者 (4/49) 发生过敏反应:2人出现轻微的皮疹,2人需要上腺素.
- 没有死亡发生;所有患者都完全康复,症状完全消失.
结论:
- 在小儿子中毒症中,SCORPIFAV治疗导致症状迅速消失.
- 没有观察到严重的过敏反应.
- 建议在子中毒风险较高的地区提供更广泛的抗毒剂.
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