在FLIP泛度测量期间内镜镇静类型不会显著影响FLIP运动性分类相对于尺度测量
Elena C Pezzino1, John E Pandolfino1, Erin Toaz2
1Kenneth C. Griffin Esophageal Center of Northwestern Medicine, Division of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
概括
在功能性光度成像探针 (FLIP) 泛度测量中使用的镇静类型与高分辨率计量相比,没有显著影响食道运动性诊断. 这证实了FLIP的泛米测量结果.
科学领域:
- 胃肠病学 胃肠病学
- 食道生理学 食道生理学
- 诊断内镜检查 诊断内镜检查
背景情况:
- 功能性光成像探针 (FLIP) 泛度测量在镇静内镜检查期间评估食道运动性.
- 结果通常与在清醒患者中进行的高分辨率测量 (HRM) 相相关.
- 镇静类型对FLIP泛度测试结果的影响需要进行调查.
研究的目的:
- 评估不同内镜镇静方法对FLIP泛度测量结果的影响.
- 为了比较FLIP泛度测量诊断与基于镇静类型的HRM诊断.
- 为了验证FLIP泛度测量用于诊断在镇静下食道运动障碍.
主要方法:
- 对454名接受FLIP泛度测和HRM的成年患者的回顾性分析.
- 根据镇静类型对患者进行分类:有意识镇静 (CS) 或监控麻醉护理 (MAC).
- HRM诊断与FLIP泛度分类在不同的镇静方案之间进行了比较.
主要成果:
- 在CS和MAC组之间在FLIP泛米分类中没有观察到HRM诊断的显著差异 (P = .306).
- 特定的FLIP泛米分类也显示,镇静类型之间没有显著差异 (P值为.202-.856).
- 在FLIP分类中,HRM诊断的比例保持一致,无论MAC中是否使用芬太尼.
结论:
- 在FLIP泛度测试中使用的镇静类型 (CS或MAC) 不会在临床上改变与HRM诊断的相关性.
- 在镇静内镜检查期间,FLIP泛度测量是诊断食道运动障碍的有效工具.
- 这些发现支持FLIP泛度计在常规临床实践中的可靠性.
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