结束产后出血导致的可预防的孕产妇死亡的研究议程:世卫组织的研究优先级练习
Caitlin R Williams1, Guervan Adnet2, Ioannis D Gallos3
1Department of Mother and Child Health, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
BMJ global health
|November 7, 2024
概括
产后出血 (PPH) 的全球研究议程优先考虑了减少孕产妇死亡的关键问题. 该议程指导未来的PPH研究和创新,以改善干预和结果.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇健康研究研究
- 全球卫生倡议全球卫生倡议
背景情况:
- 产后出血 (PPH) 是全球孕产妇死亡的主要原因.
- 在了解有效的PPH干预措施及其最佳交付方面存在重大差距.
- 一项由世界卫生组织 (WHO) 领导的倡议制定了从2023年到2030年为PPH的全球研究议程.
研究的目的:
- 为2023-2030年制定产后出血 (PPH) 的优先级全球研究议程.
- 引导未来的PPH研究和创新,以避免重复和浪费.
- 解决PPH预防,治疗和管理方面的关键知识差距.
主要方法:
- 从"柳叶刀"的PPH系列,管道分析,国际指南和专家提交的证据缺口的全面审查.
- 研究问题的分复制和分类,分为创新,实施和交叉轨道.
- 通过在线调查 (n=120) 确定优先级,使用儿童健康和营养研究倡议的方法和全球PPH峰会上的共识会议.
主要成果:
- 确定了15个高优先级的研究问题,每条轨道有5个.
- 首要优先考虑的领域包括:特兰胺酸路径的比较有效性 (创新),PPH准则采用的障碍 (实施),及时检测/第一反应策略 (跨界).
结论:
- 开发的研究议程为未来的PPH投资提供了路线图.
- 优先研究有可能在短期到中期显著影响政策和临床实践.
- 迫切需要资金来支持这些关键的PPH研究重点.
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