生殖尿路癌肝脏转移的手术管理
Guillaume Martel1, Kimberly A Bertens2, Christina Canil3
1Liver and Pancreas Unit, Department of Surgery, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada.
Hematology/oncology clinics of North America
|November 7, 2024
概括
对于具有肝转移的生殖尿路癌症,肝切除很少适用. 选择患有转移性细胞癌的患者可能会受益,但前列腺癌和膀癌转移的结果通常很差.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 泌尿生殖系统癌症研究
背景情况:
- 来自生殖尿道癌的肝转移不常见,孤立的病变很少见.
- 虽然很常见,但尿生殖系统癌症很少转移到肝脏.
研究的目的:
- 评估肝切除在转移性尿生殖系统癌症中的作用和结果.
- 为了确定可能从肝切除中受益的患者子组,在生殖尿道癌转移的背景下.
主要方法:
- 对现有文献和关于转移性细胞癌,生殖细胞瘤,前列腺癌和膀癌的肝切除的累积经验的审查.
- 分析影响结果的因素,包括疾病负担,转移时间和对全身治疗的反应.
主要成果:
- 切除肝脏可以为某些转移性细胞癌患者提供延长的生存期,特别是那些患有甲基慢性,低负担疾病的患者.
- 对于转移性生殖细胞瘤,肝切除结果取决于癌症血统和化疗反应.
- 对于从前列腺癌中转移到肝脏的预后很差,通常不建议切除肝脏.
- 对于转移性膀癌的肝切除的经验有限,肝转移是整体不良预后指标.
结论:
- 切除性尿癌转移的肝脏切除是一个复杂的决定,有不同的指示和结果.
- 手术干预在细胞癌患者的特定子集中是最有希望的.
- 对于其他泌尿生殖系统恶性瘤,由于预后不佳和证据有限,肝切除很少适用.
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