怀孕期间的饮食质量,青少年大脑形态和基于人口的队列队列中的认知表现
Yuchan Mou1, Pauline W Jansen2, Hong Sun3
1Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, The Netherlands; Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
The American journal of clinical nutrition
|November 7, 2024
概括
良好的产前营养支持儿童健康的大脑发育和认知功能. 这项研究发现,怀孕期间更高的饮食质量与更大的大脑体积和后代更好的智商指数 (IQ) 相关.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 营养科学 营养科学
背景情况:
- 怀孕期间母亲的饮食质量对于胎儿的神经发育至关重要.
- 将产前营养与长期认知结果联系在一起的机制需要进一步研究.
研究的目的:
- 调查怀孕期间母亲饮食质量与青春期前和早期后代大脑形态之间的联系.
- 确定大脑形态是否调解产前饮食质量与青少年智商 (IQ) 之间的关系.
主要方法:
- 利用了来自R世代研究的数据,包括2223个母婴双,在10岁和14岁时进行了脑部MRI扫描.
- 使用食物频率问卷和计算的饮食质量得分,评估了孕妇在怀孕期间的饮食摄入量.
- 测量后代的认知表现,使用维克斯勒智力尺度用于14岁的儿童-V.
主要成果:
- 怀孕期间母亲的饮食质量更高与10岁和14岁后代的大脑总量,白质量,灰质量和皮质下体积更大有关.
- 观察到皮层厚度,旋转和表面积的显著差异.
- 更好的产前饮食质量与更高的青少年全方位智商有关,特别是在口头理解和矩阵推理方面.
结论:
- 怀孕期间母亲的饮食质量与后代的结构性大脑发育有关.
- 产前饮食模式影响儿童的认知结果,大脑形态部分调解这种关系.
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