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Updated: Jun 8, 2025

Quantifying Agonist Activity at G Protein-coupled Receptors
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对腺A3受体的激素选择性的结构洞察

Hidetaka S Oshima1, Akiko Ogawa2, Fumiya K Sano1

  • 1Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.

Nature communications
|November 7, 2024
PubMed
概括

研究人员发现tRNA衍生的N6-异丁腺 (i6A) 作为腺氨酸A3受体 (A3R) 的选择性配体. 这一发现与N6-甲基氨酸 (m6A) 一起揭示了A3R选择性机制和潜在的药物发现.

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