认知变化量表 (CCS) 的开发和初步验证
Anne Kever1, Lauren B Heuer2, Leila Simani2
1St. Michael's Hospital, Barlo Multiple Sclerosis Centre, Toronto, ON, Canada.
Multiple sclerosis (Houndmills, Basingstoke, England)
|November 8, 2024
概括
新的认知变化量表 (CCS) 有效地测量了神经疾病患者的认知变化. 这种自我报告工具有助于跟踪疾病的进展和治疗的有效性.
科学领域:
- 神经学 神经学
- 心理测量 心理测量 心理测量
- 认知科学 认知科学
背景情况:
- 认知障碍在神经系统疾病中很普遍,需要对随时间变化的准确跟踪.
- 区分与疾病相关的认知衰退与正常衰老需要精确的测量工具.
- 现有的主观认知措施评估当前状态,而不是随着时间的推移而发生的变化,造成了研究差距.
研究的目的:
- 开发和验证一种自我报告测量方法,即认知变化量表 (Cognitive Change Scale, CCS),用于评估神经学群体感知到的认知变化.
- 评估CCS的可靠性和有效性.
- 探索CCS得分与人口因素,情绪,疲劳和客观认知表现之间的关系.
主要方法:
- 在CCS的设计和验证中采用了一种系统的混合方法方法.
- 该尺度被用在131名患有多发性硬化症的人身上,分析了人口统计,情绪和疲劳的关联.
- 46名参与者完成了认知测试电池,以将客观表现与CCS反应相关联.
主要成果:
- 17项CCS表现出良好的可靠性和有效性,并确定了四个因素结构.
- 这些因素包括一般认知,语言/执行功能,外部反和应对策略的变化.
- CCS得分与疲劳,抑郁和焦虑有积极的相关性,但与认知测试表现没有显著的相关性.
结论:
- 认知变化量表 (CCS) 显示了作为神经治疗试验中一个有价值的结果指标的潜力.
- 它捕捉感知认知变化的能力是其关键优势.
- 在不同的神经病群体中进一步验证可能会提高它的效用.
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