手术前营养评分预测肝移植后的死亡率:一项回顾性队列研究
Eun Jung Kim1,2, Jin Ha Park1,2, Soo Yeon Kim1
1Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
Anesthesia and pain medicine
|November 8, 2024
概括
通过营养风险指数 (NRI) 识别的手术前营养不良是肝移植 (LT) 后死亡率的重要预测因素. 较低的NRI分数表明LT后死亡和急性损伤风险更高.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植手术 移植手术
- 营养科学 营养科学
背景情况:
- 营养不良是已知的死亡率和发病率的风险因素.
- 研究手术前营养不良对肝移植 (LT) 结果的影响至关重要.
研究的目的:
- 确定通过客观营养指数评估的手术前营养不良是否与LT患者的术后死亡率相关.
- 确定营养不良指数,以独立预测LT后的死亡率.
主要方法:
- 440名LT患者的回顾性队列研究.
- 使用营养风险指数 (NRI),预后营养指数 (PNI) 和控制营养状况 (CONUT) 评分来评估营养状况.
- 卡普兰-梅尔曲线,日志级别测试和考克斯比例危险分析评估了死亡风险.
主要成果:
- 营养不良很普遍,影响了不同指数的66.1%至97.3%的患者.
- 营养风险指数 (NRI) 是唯一独立与3年术后死亡率相关的营养不良指数.
- 较低的NRI得分与增加的死亡率 (HR 0.97) 和更高的术后急性损伤发病率相关.
结论:
- 手术前的NRI作为肝移植后死亡率的独立预测指标.
- 在接受LT的患者中,NRI是分层死亡风险的宝贵工具.
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