儿科COVID-19的临床和流行病学特征:一项回顾性研究
Mohammadreza Mirkarimi1, Solmaz Heidari1, Ahmad Shamsizadeh1
1Department of Pediatrics, Faculty of Medicine Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran.
Health science reports
|November 8, 2024
概括
患有中度至重度疾病的COVID-19儿童患者表现出更高的营养不良,贫血和维生素D缺乏. 这些儿童的炎症标志物也较高,与轻度病例相比,他们的健康状况较差.
科学领域:
- 儿童传染病 儿童传染病
- 流行病学 流行病学
- 临床医学 临床医学
背景情况:
- 人们越来越担心2019年新冠病毒病 (COVID-19) 对儿童的影响.
- 关于伊朗儿科COVID-19的临床和流行病学特征的数据有限.
研究的目的:
- 调查儿科COVID-19的临床和流行病学特征.
- 为了确定与儿童严重COVID-19相关的风险因素和结果.
主要方法:
- 一项回顾性研究分析了伊朗阿哈瓦兹阿布扎尔医院的600名儿童COVID-19患者的医疗记录.
- 记录和分析了临床数据,人口信息,实验室结果和营养状况.
主要成果:
- 超过50%的儿童COVID-19患者是男性. 中度至严重的病例表现出明显更高水平的炎症标志物 (CRP,纤维素,d-二次体),肝酶 (ALT,GGT),功能标志物 (BUN,Cr) 和CPK.
- 中度至重度COVID-19患者的淋巴细胞和血红蛋白水平较低,发烧,干咳和长时间住院的患病率更高.
- 营养不良 (50.6%),贫血 (31.5%) 和维生素D缺乏是普遍存在的,特别是在中度至重度COVID-19的儿童中,体重不足和发育迟缓的儿童受到不成比例的影响.
结论:
- 患有中度至重度COVID-19的儿童表现出营养不良,贫血,维生素D不足/缺乏,肝脏和功能测试升高以及炎症标志物增加的更高患病率.
- 这些发现强调了营养状况和微量营养素水平在儿科COVID-19严重程度和结果中的重要性.
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