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在CBCT引导的适应性直肠增强放射治疗的轨道上,每日划分是否需要放射瘤学家?
Julien Pierrard1,2, David Dechambre2, Christel Abdel Massih2
1UCLouvain, Institut de Recherche Experimentale et Clinique (IREC), Center of Molecular Imaging, Radiotherapy and Oncology (MIRO), Brussels, Belgium.
放射治疗师 (RTTs) 可以准确地划定在线适应性放射治疗 (oART) 的直肠增强体积,减少对专家放射瘤学家 (RO) 监督的需要. 这一发现支持用于直肠癌治疗的安全高效的CBCT指导的oART工作流程.
科学领域:
- 辐射瘤学 辐射瘤学
- 医疗成像医学成像
- 癌症治疗方法 癌症治疗方法
背景情况:
- 对直肠瘤的剂量升级放射治疗是一种非手术方法.
- 在线适应性放射疗法 (oART) 纠正了分数间瘤位置错误.
- 形束计算断层扫描 (CBCT) 引导的oART需要每天对目标体积进行划分,冒着操作者之间的变化风险.
研究的目的:
- 为了比较和量化CBCT上的直肠增强体积的跨操作员和跨专业划分变异性.
- 为了评估自动划分的oART治疗计划系统体积的可变性.
- 确定不同专业群体在划分直肠增强体积方面的安全性和准确性.
主要方法:
- 15名操作人员 (专家RO,RTT,非专家RO) 在5名患者的10个CBCT上划出了直肠增强体积.
- 在不同的专业群体中评估了划界变异性,并与自动oART系统体积相比较.
- 专家RO的划分被用作参考,因为它们的变化率最低.
主要成果:
- 划界变化在上方和下方方向是最高的.
- 与专家RO相比,非专家RO,RTT和自动oART体积显示出类似的划分错误范围.
- 专家ROO展示了一致的划分结果.
结论:
- 在没有非专家RO监督的情况下,RTT可以安全地执行CBCT引导的oART的直肠增强划分.
- 结果提供了定量数据,用于准确的边际计算在直肠刺激计划.
- 该研究支持将RTT集成到oART工作流程中,用于直肠癌治疗.
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