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通过ISGylation抑制SARS-CoV-2核体蛋白质二分化,并通过病毒PLpropro对其进行反作用

Wonjin Bang1, Jaehyun Kim2, Kanghun Seo1

  • 1Department of Microbiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.

Frontiers in microbiology
|November 8, 2024
PubMed
概括

这项研究揭示,SARS-CoV-2核体 (N) 蛋白经历ISGylation,这种修饰抑制其二分化并增强对干扰素反应的敏感性. 病毒PLpro通过删除ISG15.5来对抗这种情况.

关键词:
在ISG15中,我们可以看到ISG15.PLpro PLpro 是一个专业的这就是SARS-CoV-2病毒.干扰子干扰子干扰子它是核体的核体.

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