年龄差异与心脏代谢指数与患有高血压的成年人慢性病风险之间的相关性
Yu Tao1,2,3, Tao Wang2,3,4, Wei Zhou2,3,4
1Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Journal of clinical hypertension (Greenwich, Conn.)
|November 8, 2024
概括
心脏代谢指数 (CMI) 与老年高血压患者的慢性病 (CKD) 风险有关. 在患有高血压的年轻人中没有发现这种关联,这表明年龄特定的CMI对CKD的相关性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 关于心脏代谢指数 (CMI) 和慢性病 (CKD) 风险的研究有限,特别是在高血压患者中.
- 心脏代谢指数是由腰与身高和脂质比率得出的,是代谢功能障碍的潜在指标.
研究的目的:
- 在高血压人群中调查心脏代谢指数 (CMI) 与患慢性病 (CKD) 的风险之间的关联.
- 为了确定这种关联是否在年轻和年长的高血压成年人之间有所不同.
主要方法:
- 一项涉及13,717名高血压患者的横截面研究.
- 使用腰与身高的比率和三糖与高密度脂蛋白胆固醇的比率计算CMI.
- 根据估计的膜过率 (eGFR) 定义的CKD<60mL/min/1.73m2.
主要成果:
- 在65岁以下的成年人中,CKD的患病率为4.24%,在65岁以上的成年人中为14.93%.
- 在老年高血压患者 (≥65岁) 中,CMI与CKD风险增加独立相关 (OR 1.29,95% CI:1.14,1.46).
- 在年轻的高血压患者 (<65岁) 中没有发现CMI和CKD风险之间的显著关联 (OR1.04,95%CI:0.85,1.27).
结论:
- 心脏代谢指数是老年高血压患者中CKD的独立风险因素.
- 在高血压患者中,年龄是CMI和CKD风险之间的关系的一个重要因素.
- 进一步的研究可能会探索针对老年高血压人群中CKD预防的CMI监测.
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