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Updated: Jun 8, 2025

Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes
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Differentiation of a Human Neural Stem Cell Line on Three Dimensional Cultures, Analysis of MicroRNA and Putative Target Genes

Published on: April 12, 2015

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动态mRNA稳定缓冲器在神经元分化过程中的转录激活,并由SAMD4A调节

Yuan Zhou1, Sherif Rashad1,2, Daisuke Ando1,2,3

  • 1Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.

Journal of cellular physiology
|November 8, 2024
PubMed
概括

mRNA稳定性在神经元分化和应激反应中起着至关重要的作用,作为基因表达动态的关键调节者. 这项研究揭示了神经特异性RNA稳定性动力学,并确定SAMD4A是神经元发育和氧化应激弹性中的关键调节者.

关键词:
这就是SAMD4A.在mRNA的稳定性上.在mRNA的翻译过程中,mRNA的翻译神经元分化神经元的分化氧化应激是一种氧化应激.

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