保存蔬菜消费和胃肠道癌症:一项前性研究
Wei Yu1, Yalei Ke1, Jun Lv1,2,3,4
1Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Journal of global health
|November 8, 2024
概括
在中国,食用和酸蔬菜与分别患胃癌和食道癌的风险增加有关. 限制这些保存蔬菜的摄入量可能会提供对胃肠道癌症的保护.
科学领域:
- 流行病学 流行病学
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 在中国,研究了保存蔬菜和胃肠道 (GI) 癌症之间的关联.
- 专注于两种常见类型:盐和酸的蔬菜.
- 包括食道,胃和结肠直肠癌.
研究的目的:
- 评估食用和酸蔬菜与患胃肠道癌症的风险之间的联系.
- 了解不同类型的保存蔬菜是否对癌症风险产生不同的影响.
- 提供有关制蔬菜消费的饮食建议的证据.
主要方法:
- 利用来自中国Kadoorie生物库的数据,包括510,143名成年人.
- 收集了2004-2008年期间保存蔬菜摄入频率数据,并跟踪参与者直到2018年.
- 采用Cox的比例模型来计算基于区域消费模式的胃肠道癌症危险比率.
主要成果:
- 在盐分蔬菜摄入量高的地区,消费与胃癌风险增加有关 (HR=1.17).
- 在高酸蔬菜摄入量地区,发现与食道癌症风险的剂量反应关系 (P趋势=0.013).
- 每天食用酸蔬菜,与不食用相比,食道癌的风险高出35%.
结论:
- 不同类型的保存蔬菜可能对胃肠道癌症的发展有不同的影响.
- 减少保存蔬菜的摄入量可能是防止肠道癌症的保护措施.
- 研究结果强调了饮食模式在预防癌症中的重要性.
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