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在发现和设计抗流感病毒的进步

Shixin Li1, Xi Xie2, Shaofen Zhou1

  • 1Group of Peptides and Natural Products Research, School of Pharmaceutical Sciences, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou, 510515, China.

Current medicinal chemistry
|November 8, 2024
PubMed
概括

由于频繁的病毒变化和药物耐药性,开发新的抗流感病毒是至关重要的. 本综述探讨了抗流感流行病的发现和设计策略.

关键词:
抗病毒类的抗病毒.抗流感药是一种抗流感药.自然的查自然的查.类图书馆建设 类图书馆建设合理的设计.病毒 病毒 病毒 病毒

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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