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在极度早产的婴儿中,有或没有支气管肺形的出院后的生长
Yasuka Kimoto1, Katsuya Hirata1, Shinya Hirano1
1Department of Neonatal Medicine, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan.
Pediatric pulmonology
|November 8, 2024
概括
需要家庭呼吸系统护理 (HRC) 的极度早产婴儿患有支气管肺功能障碍 (BPD) 经历了显著的增长延迟,直到5岁. 这凸显了BPD和HRC对婴儿发育的长期影响.
科学领域:
- 新生儿科学 新生儿科学
- 儿科生长与发展 儿科生长与发展
- 呼吸系统医学 呼吸系统医学
背景情况:
- 支气管肺功能障碍症 (BPD) 是一种慢性肺部疾病,会影响早产婴儿.
- 家庭呼吸系统护理 (HRC),包括家庭氧化疗法 (HOT) 和家庭机械通风 (HMV),对于患有BPD的婴儿来说,往往是出院后需要的.
- BPD和HRC对极度早产婴儿生长的长期影响尚未完全理解.
研究的目的:
- 评估支气管肺功能障碍 (BPD) 和家庭呼吸护理 (HRC) 与极度早产婴儿的生长结果之间的关联.
- 为了比较从出生到5岁的婴儿与非BPD,BPD没有HRC和BPD与HRC之间的人体测量,纠正年龄.
主要方法:
- 来自低出生体重婴儿发育调查数据的二次分析.
- 包括788个单独的非常早产婴儿,适合妊娠年龄.
- 定义 BPD 需要补充氧气或在 36 周修正妊娠年龄的呼吸系统支持.
- 从0到5岁的体重和长度测量的比较,经过年龄校正,在三个组进行了比较:非BPD,没有HRC的BPD和具有HRC的BPD.
主要成果:
- 与没有BPD或没有HRC的BPD或BPD的婴儿相比,患有BPD和HRC的婴儿在0至5岁期间体重和长度显著降低.
- 较低的妊娠年龄 (GA) 和BPD状态与3岁和5岁体重增长失败有显著的关联.
- 较低的GA与3岁和5岁的长度增长失败有显著的关联,而BPD状态在3岁时显示出显著的关联,但在5岁时没有.
结论:
- 伴随家庭呼吸护理 (HRC) 的支气管肺功能障碍 (BPD) 与极度早产婴儿 (年龄在5岁以下) 的显著增长延迟有关.
- BPD严重程度对长度增长失败的影响随着年龄的增长而减少.
- 这些发现强调了监测BPD和HRC极度早产婴儿的生长的重要性.
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