睡眠是否能缓解运动训练或复杂的精神和社会活动对慢性中风成年人的认知功能的影响? 一个随机试验的二次分析
Ryan S Falck1, Ryan G Stein1, Jennifer C Davis2
1Aging, Mobility and Cognitive Health Laboratory, Faculty of Medicine, Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.
概括
运动显著改善了脑卒中幸存者睡眠质量差的认知能力. 与对照组相比,这种干预措施有利于睡眠效率低下和自我报告睡眠质量差的人.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 睡眠科学 睡眠科学
背景情况:
- 认知能力下降是中风后的一个重大挑战.
- 运动和认知/社会丰富是改善中风后认知的已知策略.
- 睡眠对这些干预措施的缓和作用仍然不清楚.
研究的目的:
- 调查睡眠质量是否能缓和运动或丰富对慢性中风成年人的认知功能的影响.
- 为了确定基线睡眠状态对不同干预后认知结果的影响.
主要方法:
- 一个三臂随机临床试验,涉及120名55岁以上的慢性中风成年人.
- 参与者被分配到运动,丰富或平衡和音调控制组.
- 睡眠 (持续时间,效率,质量) 在基线评估时使用动图和匹兹堡睡眠质量指数 (PSQI). 使用阿尔茨海默病评估尺度加 (ADAS-Cog-Plus) 测量认知功能.
主要成果:
- 睡眠质量,特别是睡眠效率差和自我报告的睡眠质量差,调节了运动对认知的影响.
- 与睡眠质量差的对照组相比,睡眠质量差的运动参与者在6个月后显示ADAS-Cog-Plus得分有所改善.
- 对于认知丰富或睡眠持续时间,没有观察到显著的适度效应.
结论:
- 运动干预措施在提高脑卒中幸存者睡眠质量差的认知功能方面尤其有效.
- 针对中风后睡眠不足的个体进行炼可能会优化认知康复的结果.
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