阿尔茨海默病衍生的外膜囊泡加剧认知功能障碍,调节肠道微生物群,增加神经炎症和粉样β生产

Shouchao Wei1,2, Xiaochen Ma1,2, Yating Chen3

  • 1The Third Department of Neurology, Central People's Hospital of Zhanjiang, Zhanjiang, Guangdong, China.

Molecular neurobiology
|November 8, 2024
PubMed
概括

阿尔茨海默病 (AD) 外膜囊泡 (OMVs) 加快了小鼠的认知衰退和神经炎症. 这些AD衍生的OMV破坏了肠道屏障,改变了肠道微生物群,并增加了粉样β病理.

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