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Updated: Jun 8, 2025

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在TSC2缺陷细胞中增强的Gαq信号传递是其新生态行为所需的

Aurélie Tréfier1, Nihad Tousson-Abouelazm1,2, Lama Yamani3

  • 1Meakins-Christie Laboratories and Translational Research in Respiratory Diseases Program.

American journal of respiratory cell and molecular biology
|November 8, 2024
PubMed
概括

失去了TSC2基因导致LAM,这是一个由mTORC1-独立信号驱动的肺部疾病. 尿素II受体 (UT) 和Gαq信号传递是关键驱动因素,为LAM瘤提供新的治疗点.

关键词:
这是Gαqαq的意思.淋巴结核病是淋巴结核病.拉帕米的机械性标结核性硬化综合体 结核性硬化综合体尿素II受体的受体

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