在正常功能的人群中,消费植物性肉类替代品的尿反应:SWAP-MEAT试点试验
Catherine P Ward1, Matthew J Landry1, Kristen M Cunanan1
1Stanford Prevention Research Center, Stanford University School of Medicine, Palo Alto, CA.
Clinical journal of the American Society of Nephrology : CJASN
|November 8, 2024
概括
与动物肉相比,植物性肉类替代品可以通过减少食中的酸载荷和增加有益的尿道化合物来有益于脏健康. 这表明,对于患有脏疾病的人来说,有潜在的优势.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 饮食干预 饮食干预
背景情况:
- 过度食用动物肉与脏问题有关,如尿路结石病和慢性脏病 (CKD).
- 植物性肉类替代品提供植物性蛋白质,但与整个蔬菜相比,它们对健康的影响尚未完全理解.
- 一个假设提出,与动物肉相比,植物性肉减少了饮食中的酸负荷,同时增加了和的摄入量.
研究的目的:
- 研究食用植物性肉类替代品而不是动物肉对与脏健康相关的关键尿液和血清标记物的影响.
- 为了比较植物性和动物性肉类饮食之间的酸负载,和分泌量.
主要方法:
- 一个随机的8周的交叉试验 (食欲增强的植物食品肉食替代品试验的研究;NCT03718988) 涉及36名健康参与者.
- 参与者在两个8周的时间内食用植物性肉或动物肉.
- 尿液和血清样本分析了硫酸盐,,pH,,尿素 (UUN),酸盐和肌.
主要成果:
- 植物性肉类饮食与动物性肉类饮食相比,与明显较低的硫酸盐,,和UUN尿道分泌有关.
- 在植物性肉类饮食中观察到更高的尿液pH值和更高的尿酸酸与肌素的比率.
- 在植物性肉类饮食中,血清肌素水平较低,而血清二碳酸盐水平没有显著差异.
结论:
- 植物性肉类的消费,相对于动物肉类,导致尿路排泄酸前体 (硫酸盐,) 和的减少,并增加酸盐的排泄.
- 这些发现表明,植物性肉类替代品对患有脏疾病的个体有潜在的益处.
- 需要进一步的研究来证实植物性肉制品对脏健康的益处.
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