相关实验视频
Updated: Jun 8, 2025

09:26
Synthesis and Characterization of Supramolecular Colloids
Published on: April 22, 2016
9.7K
通过聚合诱导的合物聚合来制备SiO2@SiO2核心外微球的制备,表征和机制,以快速分离,使用超高性能液态染色学
Changwei Tang1, Zilong Yang1, Changle Li1
1Key Laboratory of Synthetic and Natural Functional Molecule of Ministry of Education, Institute of Modern Separation Science, Key Lab of Modern Separation Science in Shaanxi Province, College of Chemstry & Materials Science, Northwest University, Xi'an, 710127, China.
Talanta
|November 8, 2024
概括
尿素修饰通过聚合诱导的合物聚合 (PICA) 改善了芯外微球 (CSSM) 生产. 这种方法提高了外涂层和可重复性,使染色学应用的大规模合成成为可能.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 分析化学 分析化学
背景情况:
- 聚合诱导的合体聚合 (PICA) 是一种常见的方法,用于创建SiO2@SiO2核心外的微球 (CSSMs).
- 现有的PICA方法面临着不完整的外涂层和糟糕的可重复性挑战.
- 了解贝形成机制对于改善CSSM合成至关重要.
研究的目的:
- 为了研究SiO2@SiO2中贝层的形成机制,PICA准备的CSSMs.
- 为了应对CSSM生产中不完整的涂层和糟糕的可复制性的挑战.
- 优化PICA方法,以提高CSSM的产量和控制性质.
主要方法:
- 研究了芯表面的尿素修饰,以控制Zeta潜力.
- 优化了实验参数,包括pH值,温度,含水量和反应时间.
- 调整了外厚度和毛孔大小,通过改变反应时间和二氧化 sol 颗粒大小.
主要成果:
- 乌雷多修饰降低了芯的Zeta潜力,促进了在特定的Zeta潜力范围 (-20.1 mV至 -4.8 mV) 内的形成的同体沉积.
- 控制界面状态和表面潜力提高了SiO2@SiO2 CSSMs的可再生性.
- 优化条件使半规模生产的产量增加到50g,可调节外厚度和孔径大小.
- 经过八甲基三西兰 (ODS) 修改的CSSM在逆相液态染色学 (RPLC) 中表现出更高的分离效率.
结论:
- 这项研究阐明了PICA中的二氧化外形成机制,突出了Zeta潜在控制的作用.
- 改进的PICA方法克服了可重现性问题,并允许可调的CSSM属性.
- 这种优化的方法为SiO2@SiO2 CSSMs作为先进的RPLC静止相的大规模生产提供了潜力.
相关概念视频
Silica Gel Column Chromatography: Overview
1.0K
Silica gel column chromatography is a technique for separating compounds using a column packed with silica gel as the stationary phase. This method relies on differences in the polarity of compounds. Based on their polarities, compounds move between the stationary phase (silica gel) and the mobile phase (the solvent), forming discrete bands in the column.
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
1.0K
Size-Exclusion Chromatography
506
In size-exclusion chromatography (SEC), also known as molecular-exclusion or gel-permeation chromatography, molecules are separated based on their sizes. This technique is important for separating large molecules such as polymers and biomolecules. The two classes of micron-sized stationary phases encountered in SEC are silica particles and cross-linked polymer resin beads. Both materials are porous, but their pore sizes vary significantly.
Silica particles offer advantages such as rigidity,...
Silica particles offer advantages such as rigidity,...
506
High-Performance Liquid Chromatography: Introduction
1.5K
High-performance liquid chromatography(HPLC), formerly referred to as High-pressure liquid chromatography, is a powerful technique used to separate, identify, and quantify components in complex mixtures. The term "high pressure" refers to using high pressure to push the liquid mobile phase through the tightly packed columns.
In HPLC, two phases play a critical role in the separation process:
In HPLC, two phases play a critical role in the separation process:
1.5K
Supercritical Fluid Chromatography
209
Supercritical fluid chromatography (SFC) provides a beneficial substitute for gas chromatography (GC) and liquid chromatography (LC) for certain samples because it merges the top attributes of both techniques. SFC allows the separation and analysis of compounds that GC or LC does not easily manage. These compounds are traditionally nonvolatile or thermally unstable, making GC unsuitable and lacking functional groups required for HPLC analysis.
SFC utilizes a supercritical fluid mobile phase,...
SFC utilizes a supercritical fluid mobile phase,...
209
Colloidal precipitates
517
The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
517
Principles Of Column Chromatography
6.7K
The chromatography technique was first invented in 1901 by Michael S. Tswett, a Russian botanist, to separate plant pigments using organic solvents. Further, in 1941, Archer John Porter Martin and R. L. M. Synge modified the technique by packing silica gel into a column. A mixture of amino acids was then separated on the packed column using chloroform and water mixture as the mobile phase. This was the first report on column chromatography. At present, column chromatography is a widely used...
6.7K

