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Updated: Jun 8, 2025

Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte
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Use of Bisection to Reduce Mitochondrial DNA in the Bovine Oocyte

Published on: July 6, 2022

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通过体细胞核转移生产第二代绵羊克隆,使用胚胎细胞作为核捐赠体

Chunxiao Zhu1, Yiyi Liu2, Hongyang Xu3

  • 1College of Life Sciences, Inner Mongolia Agricultural University, Hohhot, 010018, China; Department of Pediatrics, Xinqiao Hospital, Army Medical University, Chongqing, 400073, China; Inner Mongolia Key Laboratory of Biomanufacture, Hohhot, 010018, China.

Theriogenology
|November 8, 2024
PubMed
概括

胚胎细胞与纤维细胞不同,为体细胞核转移 (SCNT) 克隆提供了更大的基因组稳定性. 使用基因编辑绵羊羊胎细胞显著提高克隆后代的胎儿存活率.

关键词:
胚胎细胞是胚胎细胞的组成部分.核捐赠细胞细胞的核供体细胞.复克龙 (Reclone) 是一个复克龙.人体细胞核转移 (SCNT)幸存率 幸存率 幸存率

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