表面工程磁性纳米结构在癌症治疗中的最新进展和当前状态
Bijaideep Dutta1, K C Barick1, P A Hassan1
1Chemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India.
Advances in colloid and interface science
|November 8, 2024
概括
磁纳米结构 (MNSs) 提供先进的癌症疗法,将诊断和治疗结合起来,进行精确的,非侵入性的治疗. 它们的多功能特性使得从药物输送到多式成像和高温症的应用成为可能.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术 纳米技术
- 在瘤学瘤学.
背景情况:
- 癌症治疗术结合了诊断和治疗,以改善患者的治疗结果.
- 磁纳米结构 (MNSs) 具有独特的特性,非常适合于theranostic应用.
- 目前的癌症管理寻求更精确,更少的侵入性治疗方式.
研究的目的:
- 提供MNS在癌症中的最先进的治疗应用的概述.
- 突出MNS合成和表面工程对疗效的重要性.
- 讨论MNS用于癌症管理的临床转化方面的进展,机遇和挑战.
主要方法:
- 关于MNSs用于癌症治疗的当前文献的综述.
- 对MNS的合成方法和表面功能化策略的分析.
- 探索MNS与诊断和治疗药物的整合.
主要成果:
- 许多MNS表现出显著的治疗潜力,包括药物输送,磁性高温和先进的成像.
- 表面工程和精确的合成对于优化MNS性能至关重要.
- 可以将MNS与放射性同位素或光探针集成在一起,用于多式成像.
结论:
- 多功能癌症神经元是开发多功能癌症神经元药物的有希望的平台.
- 对合成,功能化和临床翻译的进一步研究对于实现MNSs的全部潜力至关重要.
- 基于MNS的治疗疗法为更有效和个性化的癌症治疗提供了途径.
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