了解统计群体和推论的理解
1Department of Radiology, Service of Neuroradiology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.
Neuro-Chirurgie
|November 8, 2024
概括
临床研究中的"人口"一词令人困惑,并且经常被滥用,导致研究设计和解释中的错误. 研究人员应该节制地使用这个术语,以避免对概括和推断的误解.
科学领域:
- 临床研究 临床研究
- 生物统计学 生物统计学
- 流行病学 流行病学
背景情况:
- 在临床研究和统计学中",人口"一词往往是模两可的和多方面的.
- 误用"人口"一词可能会导致研究设计,分析和解释的重大错误.
研究的目的:
- 审查人口的各种概念.
- 检查人口和统计推理之间的关系.
- 为了澄清人口是指个人,变量还是理论构造.
主要方法:
- 对不同种群概念的审查.
- 分析它们与统计推理方法的联系.
- 探索它们对人,变量和理论构造的应用.
主要成果:
- 基于设计和基于模型的统计推断之间的区别.
- 人群很少在临床研究中引用实际的患者.
- 超级人口,伪人口和统计人口代表理论或数学构造,导致分析复杂性.
- 目标人群经常被错误地等同于资格标准,当真实人口缺席时.
- 从研究对象推广到未来患者的归纳问题由于语义模两可,仍然未解决.
结论:
- 术语"人口"经常模糊而不是澄清与临床研究中的概括和推断有关的问题.
- 由于它可能导致错误和误解,在临床研究中应尽量减少使用"人口"一词.
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