干白素-1β在人体造血原生细胞中诱导受过训练的先天免疫力 in vitro

Daniela Flores-Gomez1, Willemijn Hobo2, Diede van Ens2

  • 1Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, Gelderland, the Netherlands.

Stem cell reports
|November 8, 2024
PubMed
概括

干白素-1β (IL-1β) 暴露在体外重新编程人类造血原生细胞 (HPC),诱导训练免疫力. 这种表观遗传和代谢重编程增强了单细胞的炎症反应,并促进了动脉动脉道.

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