在心胸移植患者群体中,mycobacteroides的爆发和缓解:自来水的问题
S N Rathod1, R T Weber1, A A Salim2
1Department of Healthcare Epidemiology and Infection Prevention, Northwestern Memorial Hospital, Chicago, IL, USA.
The Journal of hospital infection
|November 8, 2024
概括
在心胸移植患者中,Mycobacteroides综合体 (M. abscessus) 的医院爆发增加. 实施无菌水预防措施和教育显著降低了M.的发生率.
科学领域:
- 传染病流行病学 传染病流行病学
- 医疗保健相关的感染
- 移植医学 移植医学 移植医学
背景情况:
- 医院爆发的Mycobacteroides综合体 (M. abscessus) 对免疫功能低下的患者构成重大风险,特别是在心胸移植群体中.
- 在住院心胸移植环境中观察到与医疗保健相关的M.病例的增加.
研究的目的:
- 在心胸移植单位调查M.综合体的爆发.
- 描述实施的缓解策略,以控制疫情爆发和减少发病率.
主要方法:
- 对疫情爆发前 (2018年3月至2020年12月) 和疫情爆发期间 (2021年1月至2022年6月) 的M.病例临床数据的回顾性分析.
- 一个多学科团队领导了疫情调查,并制定了缓解策略.
- 实施无菌水防护措施,为工作人员提供有针对性的教育.
主要成果:
- 在疫情爆发期间,与医疗保健相关的M.的发病率从每10,000个患者日中从0.11增加到0.24个病例.
- 心胸移植患者受影响的比例从11%增加到58%.
- 随着无菌水的预防措施,发病率下降到每10,000个患者日中的0.06例.
结论:
- 教育举措和严格的无菌水协议有效地减少了这种移植人群中M.的发生率.
- 监测,教育和水资源管理对于预防肺移植中心的M.疹疫情至关重要.
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