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Updated: Jun 8, 2025

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay

Published on: March 10, 2020

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作为信号传递的分子决定因素,阿雷斯-G蛋白合受体复合体的结构可塑性

Angelo Felline1, Luca Bellucci2, Vanessa Vezzi3

  • 1Dipartimento di Scienze della Vita, Università di Modena e Reggio Emilia, via Campi 103, 41125 Modena, Italy.

International journal of biological macromolecules
|November 8, 2024
PubMed
概括

G蛋白结合受体 (GPCR) 通过逮捕素的调节非常动态. 这项研究揭示了β-arrestin 1 (βarr1) 灵活性和集体运动如何决定其与V2压缩素受体 (V2R) 等GPCR的合.

关键词:
在被捕后,我被捕了.在GPCRs中,GPCRs是指GPCR.分子建模,模拟和模拟.

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