过敏接触性皮肤炎对儿童的赫西丁
Luis Moral1, Alicia Moral2, Laura Murcia3
1Doctor Balmis General University Hospital, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; lmoralg@gmail.com.
Allergologia et immunopathologia
|November 8, 2024
概括
对赫西丁过敏接触性皮肤炎在儿童中很少见. 用2%的赫西丁溶液进行的重复开放应用试验 (ROAT) 是最敏感的诊断方法.
科学领域:
- 儿科过敏和免疫学
- 皮肤病学 皮肤病学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 对赫西丁的过敏反应在儿童群体中不常见.
- 在儿童中识别赫西丁诱导的过敏接触性皮肤炎 (ACD) 的诊断方法尚未成熟.
研究的目的:
- 报告一系列儿科患者对赫西丁过敏的病例.
- 为了比较儿童中ACD的各种诊断测试的疗效.
主要方法:
- 一个案例系列的九个孩子怀疑赫西丁过敏.
- 六名儿童接受过敏评估,包括刺痛测试,皮内测试,贴片测试和重复开放应用测试 (ROAT).
主要成果:
- 在9名儿童中,有7名 (78%) 在5岁之前出现症状.
- 所有六名被评估的儿童的刺测试均呈阴性.
- 补丁测试在六个中的五个中呈阳性,而使用2%氧胺醇溶液的ROAT在所有六个中呈阳性.
结论:
- 儿科的赫西丁诱导的ACD是罕见的,并且难以诊断.
- 临床医生应该怀疑小儿伤口未能改善的赫西丁ACD.
- 在这个队列中,ROAT在检测赫西丁ACD方面表现出比补丁测试更高的灵敏度.
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