与欧洲宿主人口相比,少数民族的2型糖尿病并发症:系统性审查和元分析
Joline W J Beulens1,2,3, Felix Reichelt1, Sharon Remmelzwaal1,2,3,4
1Epidemiology and Data Science, de Boelelaan 1117, Amsterdam UMC, Amsterdam, The Netherlands.
BMJ open diabetes research & care
|November 8, 2024
概括
在欧洲,患有2型糖尿病的少数民族的死亡率和大血管风险较低,但与宿主人口相比,脏病和视网膜病变的风险更高. 这些发现有助于识别高风险群体,并制定有针对性的干预措施.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 糖尿病研究 糖尿病研究
背景情况:
- 2型糖尿病 (T2D) 在全球范围内不成比例地影响少数民族人口.
- 了解T2D并发症差异对于欧洲的公平医疗保健至关重要.
- 现有的研究往往缺乏在欧洲环境中对少数民族和东道主群体进行直接比较.
研究的目的:
- 系统地审查和对少数民族和欧洲宿主群体之间的T2D并发症差异进行元分析.
- 量化死亡率,大血管和小血管并发症以及精神疾病的风险.
- 为欧洲各种T2D患者群体提供公共卫生策略和临床指导方针.
主要方法:
- 按照PRISMA指南进行系统审查和元分析.
- 在多个数据库中搜索了欧洲研究,比较少数民族和东道主群体的T2D并发症 (直到2024年7月1日).
- 使用随机效应模型和评估58项纳入研究的偏差风险的风险估计.
主要成果:
- 少数民族人口显示所有原因死亡率 (RR 0.70) 和大血管并发症 (RR 0.72) 的风险较低.
- 南亚人有相似的宏观血管风险,但主要心血管不良事件的风险略高.
- 观察到微血管并发症的风险增加,特别是病 (前性研究中的RR 1.50) 和视网膜病变;精神障碍中没有种族差异.
结论:
- 在欧洲,患有T2D的少数民族的死亡率和大血管风险一般都降低了.
- 对脏病和视网膜病的更高风险需要有针对性的查和管理.
- 研究结果支持制定定制干预措施和指导方针,以解决T2D结果中的种族差异.
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