儿科重症监护室中与药物相关的问题:患病率,危险因素和临床药剂师的干预
Nasrin Shirzad-Yazdi1,2, Sajjad Taheri1, Afsaneh Vazin2
1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
BMC pediatrics
|November 8, 2024
概括
伊朗的儿科重症监护室 (PICU) 在儿童中经常出现与毒品有关的问题 (DRP),最常见的是低于最佳的治疗和安全问题. 干预措施的接受度很高,这突出了需要谨慎的剂量,特别是在功能障碍.
科学领域:
- 儿科重症监护室的儿童重症监护室
- 临床药房 临床药房
- 药物监督 药物监督 药物监督
背景情况:
- 与药物相关的问题 (DRP) 在重症监护室 (ICU) 普遍存在,增加了药物不良事件和医疗保健成本.
- 由于生理差异,儿童患者特别容易受到DRP的影响.
- 这项研究涉及伊朗南部儿科重症监护室 (PICU) 中DRP的高发病率.
研究的目的:
- 确定伊朗南部的手术和医疗PICU入院的儿科患者中DRP的患病率.
- 确定这种脆弱人群中DRP的类型和原因.
- 评估DRP临床药剂师干预措施的接受率.
主要方法:
- 在伊朗的Shiraz医学科学大学Namazi医院进行了一项横截面研究 (2022年6月至2023年3月).
- 从医疗和外科PICU的儿科患者收集数据,使用欧洲制药护理网络的DRP表格 (v8.01).
- 结果被重点小组验证并使用SPSS进行统计分析.
主要成果:
- 在323名儿科患者中,有57%的人至少经历过一次DRP.
- 低于最佳的药物治疗 (41.13%) 和治疗安全问题 (38.53%) 是最常见的DRP.
- 药物相互作用 (36.26%) 是主要原因;处方药和抗药的数量是重要的因素. 97%的药剂师干预措施被接受.
结论:
- PICU患者,特别是儿童,面临着DRP的高负担.
- 优化药物剂量调整对于儿科患者至关重要,特别是患有功能障碍的儿科患者.
- 临床药剂师的干预措施在PICU的DRP管理中是有效的,并且得到了很好的接受.
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