食物中的真菌毒素:癌症风险和控制策略
Alice N Mafe1, Dietrich Büsselberg2
1Department of Biological Sciences, Faculty of Sciences, Taraba State University, Main Campus, Jalingo 660101, Taraba State, Nigeria.
Foods (Basel, Switzerland)
|November 9, 2024
概括
来自真菌的真菌毒素污染食品,造成健康风险并增加癌症风险. 本次审查涵盖了它们的起源,检测,控制以及需要全球战略来确保食品安全.
科学领域:
- 食品科学 食品科学 食品科学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 菌毒素是污染粮食作物的真菌毒素,对食品安全和人类健康构成重大风险.
- 暴露于真菌毒素与各种不良健康影响有关,包括增加癌症风险.
研究的目的:
- 审查主要真菌毒素对人类健康的起源,意义和影响,重点关注癌症风险.
- 检查目前用于毒素检测的方法和污染控制策略.
- 在真菌毒素管理方面确定挑战和未来的研究方向.
主要方法:
- 关于真菌毒素,其来源和受影响的食物的综合文献综述.
- 分析致癌机制和流行病学证据,将菌毒素暴露与癌症联系起来.
- 分析技术 (HPLC,GC-MS,MS,ELISA) 和控制策略 (收获前后) 的评估.
主要成果:
- 主要的真菌毒素 (亚毒素, ochratoxins, fumonisins, zearalenone, patulin) 通过它们的来源和相关的食物来确定.
- 致癌机制和流行病学数据强调了菌毒素暴露与癌症之间的联系.
- 有效的检测和控制策略存在,但在灵敏度,成本和实施方面面临挑战.
结论:
- 菌毒素污染是一个关键的全球食品安全问题,需要强有力的检测和控制措施.
- 对创新分析技术,气候变化影响和控制策略的进一步研究至关重要.
- 全球合作和新兴技术对于减轻真菌毒素风险和提高食品安全至关重要.
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