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相关概念视频

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

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相关实验视频

Updated: Jun 19, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
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使用光学一致性断层扫描提取光学元件信息的方法.

Jiucheng Nie1,2,3,4, Yukun Wang1,2,3,4, Dacheng Wang1,2,3,4

  • 1Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China.

Sensors (Basel, Switzerland)
|November 9, 2024
PubMed
概括
此摘要是机器生成的。

这项研究引入了一种新的方法,用于同时测量光学薄膜厚度,曲率和缺陷,使用光谱域光学连贯性断层扫描 (SD-OCT). 这一进步提高了光学元件质量测试的高精度和效率.

关键词:
曲率测量的曲率测量多层薄膜是多层的.在光谱域的OCT上.测量厚度的测量方法

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科学领域:

  • 光学工程是指光学工程.
  • 计量学 计量学 计量学
  • 非破坏性测试 不破坏性测试

背景情况:

  • 精确测量光学薄膜参数 (厚度,曲率,缺陷) 对于质量控制至关重要.
  • 现有的方法很难同时提取这些多个参数.
  • 光谱域光学连贯性断层扫描 (SD-OCT) 为光学元件分析提供了非侵入性成像.

研究的目的:

  • 开发和验证一种高精度和高效的方法,用于同时测量薄膜厚度,曲率和缺陷.
  • 增强SD-OCT在光学薄膜计量方面的能力.
  • 提高光学元件的质量和性能测试.

主要方法:

  • 为SD-OCT提出了一个错误校正模型,以补偿延迟差异,场曲率和偏差.
  • 实施了直方图均等灰色拉伸 (IAH-GS) 来处理薄膜中的强反射.
  • 开发了一个窗口值切断算法,用于在OCT图像中准确识别缺陷和边界.

主要成果:

  • 实现了同时测量光学薄膜的厚度,曲率和缺陷.
  • 显示了1.924微米的厚度测量精度.
  • 在校准和名义曲率测量之间保持1%的差异.
  • 系统功能包括4.508mm的测量深度和5.69μm的分辨率.

结论:

  • 拟议的SD-OCT方法可以同时,准确和高效地测量光膜厚度,曲率和缺陷.
  • 这种技术显著推进了光学薄膜测试,提高了生产率和产品质量.
  • 纠错模型和算法提高了SD-OCT在光学计量学中的可靠性和适用性.