在乳清蛋白分离中超过的聚硫浸氧化的研究
Tutik Sriani1, Muslim Mahardika2, Budi Arifvianto2
1Department of Research and Development, PT. Global Meditek Utama-IITOYA, Sardonoharjo, Ngaglik, Sleman, Yogyakarta 55581, Indonesia.
Polymers
|November 9, 2024
概括
酸 (HA) 改性多硫 (Psf) 超膜显示了增强的蛋白质分离. 这种具有成本效益的方法提高了乳清蛋白应用的流量和选择性.
科学领域:
- 材料科学 材料科学 材料科学
- 化学工程是化学工程的重要组成部分.
- 分离科学 分离科学
背景情况:
- 聚硫 (Psf) 超膜对于蛋白质分离至关重要.
- 提高膜性能,特别是流量和选择性,对于工业应用至关重要.
- 氧酸盐 (HA) 被探索为改性剂,以改善膜性质.
研究的目的:
- 用HA修改Psf超膜,以改善蛋白质分离.
- 调查HA结合对膜结构,水友性和防性质的影响.
- 为了评估HA修饰膜在乳清蛋白分离中的性能.
主要方法:
- 使用湿相逆转方法与NMP溶剂制备了Psf超透平板膜.
- 在膜制备过程中加入了Hydroxyapatite (HA) 粉.
- 用扫描电子显微镜 (SEM) 分析了膜形态.
- 使用牛血清白蛋白 (BSA) 和lyszyme来评估蛋白质分离性能.
主要成果:
- HA 在Psf矩阵中均分布.
- 纳入HA增加了透性流量,达到65 LMH/bar的高峰,HA的重量为0.3%,改善了38%.
- BSA和lyszyme的蛋白质排斥率分别达到97.2%和73%.
- 修改后的膜表现出增强的水友性 (接触角度从66°降低到53°) 和改善的防性质.
- 与原生膜相比,混合膜在酶分离方面表现出更高的选择性.
结论:
- 酸修饰是一种简单,经济的方法,可以提高Psf超膜的性能.
- 修改后的膜为乳清蛋白分离提供了更好的流量和选择性,而不会影响效率.
- 这种方法为蛋白质分离工业促进了膜生产的可扩展性.
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