皮肤衰老的不同途径:客观仪器评估
Noah Musolff1,2, Carmen Cantisani1, Stefania Guida3
1Dermatology Clinic, Department of Internal, Anesthesiologic and Cardiovascular Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.
Diagnostics (Basel, Switzerland)
|November 9, 2024
概括
这项研究使用了非侵入性成像来区分肌肤过度衰老和肌肤衰老. 在面部皮肤中,VISIA®和D-OCT有效地识别了明显的老化亚型和血管性模式.
科学领域:
- 皮肤病学 皮肤病学
- 医疗成像医学成像
- 老年学是指老年学的学科.
背景情况:
- 皮肤衰老呈现为明显的过度缩 (纹,皮肤质地) 和缩 (稀薄,血管性) 现象型.
- 了解这些亚型对于有针对性的皮肤病干预至关重要.
- 非侵入性成像提供了一种有希望的方法来表征老化皮肤.
研究的目的:
- 为了区分高缩和缩的面部衰老亚型.
- 评估VISIA®和动态光学连贯性断层扫描 (D-OCT) 在表征皮肤衰老方面的有效性.
- 为了确定潜在的中间衰老表型.
主要方法:
- 对40名接受非侵入性面部成像检查的患者 (60至75岁) 的回顾性分析.
- 使用VISIA®进行紫外线点和红色区域评估,以及D-OCT用于血管性和皮肤密度.
- 根据VISIA®的研究结果将受试者分为PIGM,RED,CONTROL和PIGM + RED分组.
主要成果:
- 在VISIA®红色区域得分和D-OCT血管密度之间发现了强烈的相关性.
- 在紫外线斑点 (PIGM组) 的区域观察到较高的纹数量.
- 低衰减系数和皮肤密度与高红色区域和低紫外线斑点有关.
结论:
- 非侵入性成像设备对于评估面部衰老和区分亚型是有效的.
- VISIA®和D-OCT成功地区分了衰老的表型,并评估了血管性.
- 除了传统的高缩和缩亚型外,还确定了两种中间衰老类型.
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