评估微循环功能障碍通过测量皮下组织氧和使用近红外光谱在患有循环衰竭的患者近红外光谱
Jun Sato1, Atsushi Sakurai1, Shingo Ihara1
1Department of Acute Medicine, Division of Emergency and Critical Care Medicine, Nihon University School of Medicine, 30-1 Oyaguchi Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
Diagnostics (Basel, Switzerland)
|November 9, 2024
概括
近红外光谱学 (NIRS) 评估了血液循环衰竭患者的微循环. 皮下膝关节氧和度 (rSO2) 表示器官损伤,与SOFA分数相关.
科学领域:
- 关键护理医学 关键护理医学
- 生物医学工程 生物医学工程
- 生理学 生理学 生理学
背景情况:
- 血液循环不良导致高死亡率,需要对微循环进行评估.
- 血液动力学改善并不总是解决持续的微循环功能障碍.
- 近红外光谱 (NIRS) 提供了一种方法,通过皮下区域组织氧和 (rSO2) 来评估微循环.
研究的目的:
- 评估NIRS测量的rSO2在评估患有循环衰竭的患者微循环功能障碍时的有用性.
- 为了确定膝盖rSO2与顺序器官衰竭评估 (SOFA) 分数之间的相关性.
主要方法:
- 在健康志愿者和ICU患者中,NIRS被用于测量多个部位的rSO2,包括膝盖.
- 循环衰竭是由特定的缩血压和乳酸值来定义的.
- 展望性,单中心研究,比较在ICU入院时患有和没有循环衰竭的患者.
主要成果:
- 健康的志愿者在测量地点显示约58%的rSO2.
- 与没有循环衰竭的患者相比,患有循环衰竭的患者表现出明显较低的膝盖rSO2.
- 在ICU的最初几天,膝盖rSO2与SOFA得分有显著的负相关性.
结论:
- 皮下膝盖rSO2作为微循环功能障碍的有价值指标.
- 膝盖rSO2与SOFA评分相关,反映了循环衰竭中器官损伤的严重程度.
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