表面扩散系数值和表面扩散系数比作为前列腺癌攻击性预后因素的作用
Arvids Buss1,2, Maija Radzina1,2,3, Mara Liepa1,2
1Radiology Research Laboratory, Riga Stradins University, LV-1007 Riga, Latvia.
Diagnostics (Basel, Switzerland)
|November 9, 2024
概括
表面扩散系数 (ADC) 值与前列腺癌的格里森得分有很强的相关性,有助于确定瘤的攻击性和潜在的PI-RADS得分.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 前列腺癌是男性常见的恶性瘤.
- 准确评估病变的攻击性对于治疗决策至关重要.
- 定量核磁共振,特别是ADC值,在预测瘤行为的方面表现有前途.
研究的目的:
- 评估ADC值与前列腺癌攻击性之间的相关性.
- 为了确定ADC值是否可以帮助预测格里森等级组.
主要方法:
- 对398名前列腺癌患者的回顾性分析.
- 多参数MRI与DWI ADC值测量 (b=50,1000). 通过多参数MRI测量DWIADC值 (b=50,1000). 通过多参数MRI测量DWIADC值 (b=50,1000). 通过多参数MRI测量DWIADC值 (b=50,1000). 通过多参数MRI测量DWIADC值 (b=50,1000). 通过多参数MRI测量DWIADC值 (b=50,1000).
- 将ADC值与从激进前列腺切除术中得出的格里森等级组进行比较.
主要成果:
- 在ADC和格里森得分之间观察到显著的负相关性 (rs = -0.846,p < 0.001).
- 对于临床显著的前列腺癌,ROC分析得出AUC为0.958,ADC值为758μm2/s.
- 绝对ADC值与ADC比率一样有效.
结论:
- DWI ADC值与格里森得分相反相关.
- ADC值在评估前列腺癌的攻击性方面表现出强大的能力.
- ADC指标可能有助于PI-RADS类别分配.
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