在接受内镜下垂体腺手术的患者中长期的生活质量
Narin Nard Carmel Neiderman1, Shay Kaufman1, Ran Bilaus1
1Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Affiliated to Tel Aviv University, Tel Aviv 6423906, Israel.
Journal of clinical medicine
|November 9, 2024
概括
透视下垂体瘤切除维持了鼻功能和瘤恢复的高长期生活质量 (QOL). 手术后的QOL在5年内保持稳定,瘤类型或手术因素没有显著影响.
科学领域:
- 神经外科 神经外科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
背景情况:
- 骨底部病变的内镜内外科手术具有较少的侵入性,具有有利的短期生活质量 (QOL).
- 在垂体瘤切除后,关于鼻功能和与瘤相关的QOL的长期数据有限.
研究的目的:
- 为了评估长期鼻腔和瘤相关的QOL在内镜内切除垂体瘤后的患者.
- 为了确定手术后质量生活不良的预测因素.
主要方法:
- 对43名因垂体腺瘤而接受跨形手术的患者进行前性队列研究 (2014-2021年).
- 患者在手术前和手术后的1,3,3年和3-5年完成了前头骨基底疾病特异性QOL (ASBS-Q) 和鼻结局测试22 (SNOT-22) 问卷.
- 收集和分析了临床数据.
主要成果:
- 在5年的随访期间,没有观察到与瘤相关的QOL (ASBS-Q,SNOT-22) 显著下降.
- 在1,3年和5年,SNOT-22得分与基线没有统计学上显著的变化.
- 瘤特征,手术因素和内分泌缓解没有显著影响QOL.
结论:
- 在5年的时间里,内镜下垂体损伤切除导致持续的高鼻腔和瘤相关的QOL.
- 需要进一步的多中心研究和更大的队列来验证这些发现.
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