在椎脊髓损伤中,皮层脊髓节省
Clarissa Pedrini Schuch1, Lazar I Jovanovic2, Gustavo Balbinot3,4,5
1MyantX Corp, Mississauga, ON L5K 2L1, Canada.
Journal of clinical medicine
|November 9, 2024
概括
椎脊髓损伤 (cSCI) 影响手的功能. 保持皮质脊柱管 (CST) 完整性是上肢恢复的关键,类似于中风的结果.
科学领域:
- 神经科学是一个神经科学.
- 脊髓损伤研究 脊髓损伤研究
- 神经学 神经学
背景情况:
- 椎脊髓损伤 (cSCI) 经常导致上肢功能缺陷显著.
- 大脑与手的连接完整性是已知的中风患者康复的预测因素.
- 在cSCI中,这些神经连接的预测价值是一个正在积极研究的领域.
研究的目的:
- 审查最近关于cSCI中皮质脊柱管 (CST) 完整性的预测价值的发现.
- 突出 CST 节约作为一个潜在的生物标志物,用于上肢康复后cSCI.
- 讨论当前评估指标的局限性,并介绍新兴的指标.
主要方法:
- 透视性文章回顾了来自大量cSCI个体的近期研究结果.
- 分析数据,证明皮质脊髓管 (CST) 完整性的预测能力.
- 批判性评估既有指标 (例如,圣节节约,中枢综合征) 和新兴指标 (例如,组织桥梁).
主要成果:
- 有证据表明,皮质脊柱管 (CST) 完整性是cSCI上肢恢复的重要预测因素.
- 在cSCI中,CST节省显示出与在中风恢复中观察到的类似的预测能力.
- 像神圣节约这样的既定指标在预测功能恢复方面存在局限性.
结论:
- 皮质脊髓管 (CST) 完整性是预测上肢cSCI后功能恢复的关键生物标志物.
- 像组织桥梁这样的新兴指标对评估脑脊髓连接完整性显示出希望.
- 需要进一步的研究来完善和验证cSCI的新生物标志物.
相关概念视频
Direct Motor Pathways
1.8K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
1.8K
Indirect Motor Pathways
1.4K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.4K
Spinal Cord: Cross-sectional Anatomy
1.7K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray...
Gray Matter and its Components
Central to the gray...
1.7K
Major Somatic Sensory Pathways
898
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
898
Spinal Nerves: Plexus I
772
Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
772
Overview of Somatic Sensory Pathways
4.2K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.2K


