相关实验视频
Updated: Jun 7, 2025

04:39
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
1.6K
88只甲状腺过高的猫的红细胞变化
Olga Gójska-Zygner1, Grzegorz Kotomski1, Joanna Gajger1
1LABROS Specjalistyczna Przychodnia Weterynaryjna, Św. Bonifacego 92, 02-940 Warsaw, Poland.
Animals : an open access journal from MDPI
|November 9, 2024
概括
猫类甲状腺功能障碍会导致红细胞 (RBC) 的变化,包括红细胞和微细胞. 研究表明,受影响猫的红细胞计数和平均体积 (MCV) 之间存在负相关性.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 内分泌学 在内分泌学.
- 血液学 血液学 血液学
背景情况:
- 有限的研究存在于猫类甲状腺功能障碍的红细胞变化.
- 同时出现的疾病和不同的分析仪有助于研究差异.
研究的目的:
- 分析88只没有并发疾病的甲状腺功能高的猫的红细胞 (RBC) 变化.
- 确定红细胞变化与甲状腺素 (T4) 度,年龄和性别等因素之间的关联.
主要方法:
- 研究了88只甲状腺功能高的猫.
- 分析了红细胞的参数.
- 评估与血清T4,年龄和性别的相关性.
主要成果:
- 观察到红细胞瘤 (12只猫),贫血 (4只猫),巨细胞瘤 (2只猫) 和微细胞瘤 (3只猫).
- 微细胞瘤发生在患有红细胞瘤的猫身上.
- 在红细胞计数和平均体积 (MCV; r = -0.57, p < 0.001) 之间发现了负相关性.
结论:
- 红细胞瘤可能是对甲状腺过高猫的微细胞瘤发育的反应.
- 红细胞计数和MCV相关性可能来自改变的肝素,红蛋白和甲状腺刺激激素 (TSH) 作用.
相关概念视频
Disorders of Erythrocytes
863
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
863
Factors Affecting Erythropoiesis
3.1K
The cardiovascular system regulates the number of erythrocytes in the bloodstream to ensure optimal oxygen transport. It also prevents over-proliferation of these cells, which helps to maintain blood viscosity and flow rate.
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
3.1K
Synthesis and Regulation of Thyroid Hormones
4.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.2K
Erythropoiesis
4.1K
Red blood cells (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia,...
4.1K

