饮食抗氧化剂和天然化合物在预防血栓形成和心血管疾病方面
Elvira Giurranna1, Francesca Nencini1, Alessandra Bettiol1
1Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Firenze, 50134 Firenze, Italy.
International journal of molecular sciences
|November 9, 2024
概括
饮食干预和抗氧化剂补充剂可以帮助减少氧化应激,防止血块形成. 这些非药理学方法对心血管健康和控制血栓形成有前途.
科学领域:
- 心血管科学 心血管科学
- 营养科学 营养科学
- 氧化压力研究研究 氧化压力研究
背景情况:
- 反应性氧物种 (ROS) 与内皮功能障碍,血小板激活和凝血有关,导致血栓形成.
- 氧化应激在血栓事件和心血管疾病的发病过程中发挥着关键作用.
- 对减轻氧化应激及其血管后果的非药理策略越来越感兴趣.
研究的目的:
- 审查饮食干预和抗氧化剂补充剂在减少氧化损伤方面的潜力.
- 评估各种饮食和补充剂在预防血栓事件方面的有效性.
- 突出最近在使用营养方法预防血栓形成和心血管健康方面的进展.
主要方法:
- 对食模式和抗氧化剂补充剂的体外,体外和临床研究的审查.
- 对地中海饮食,DASH饮食和饮食对氧化应激标志物影响的分析.
- 检查包括黄素,和多在内的抗氧化剂补充剂对它们对血栓形成的影响.
主要成果:
- 像地中海,DASH和性饮食这样的饮食模式在改善氧化应激标志物方面表现有前途.
- 富含抗氧化剂的补充剂 (黄素,,多) 表明对脂质谱和炎症有有益影响.
- 这些干预措施总体上显示出减少氧化损伤和调节导致血栓形成的因素的潜力.
结论:
- 饮食策略和抗氧化剂补充剂是治疗血栓形成的可行的非药物治疗方法.
- 将这些营养干预措施整合到预防和治疗策略中可以改善心血管健康.
- 进一步的研究对于个性化干预和确认患者的长期结果至关重要.
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