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Updated: Jun 7, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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MDH2 通过稳定 GPX4 通过 Ferroptosis 逃避促进肝细胞癌的生长

Wenjia Yu1, Yingping Li2, Chengchang Gao1

  • 1The MOE Basic Research and Innovation Center for the Targeted Therapeutics of Solid Tumors, School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang 330031, China.

International journal of molecular sciences
|November 9, 2024
PubMed
概括

酸脱酶2 (MDH2) 调节铁亡,这是一个细胞死亡过程. 在肝细胞癌 (HCC) 中抑制MDH2可促进铁亡,阻碍瘤生长,并提供新的治疗策略.

关键词:
在HCC中,HCC是HCC.MDH2MDH2 MDH2 MDH2 MDH2 MDH2 MDH2 MDH2 MDH2铁性化 (ferroptosis) 是一种瘤进展的进展情况

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