封装可以提高人类中多的生物利用性吗? 一个简短的回顾 基于活体人体研究
Ali Ali Redha1,2, Chamali Kodikara3,4, Daniel Cozzolino2
1The Department of Public Health and Sport Sciences, University of Exeter Medical School, Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.
Nutrients
|November 9, 2024
概括
封装增强了多单个化合物如黄素的生物可用性,但对多组显示不一致的结果. 需要进一步的研究,特别是功能性食品.
科学领域:
- 营养科学 营养科学
- 食品科学与技术 食品科学与技术
- 药理学 药理学是指药理学的学科.
背景情况:
- 多提供健康益处,但其生物可用性较低,限制了其有效性.
- 封装保护聚在消化过程中免受降解,改善它们的输送.
- 关于增强生物利用性的现有证据主要来自体外研究,缺乏体内验证.
研究的目的:
- 审查体内人体研究对封装在改善多生物可用性的疗效.
- 评估当前关于封装技术对多醇吸收和疗效的影响的临床证据.
主要方法:
- 在人体体内实体研究的系统审查,调查封装的多.
- 对临床数据的分析,重点是囊聚醇消费后的生物可用性标志物.
- 评估涉及特定多源 (葡萄末,可可,蓝) 和单个化合物 (fisetin,hesperidin,curcumin) 的研究.
主要成果:
- 封装有效地改善了单个多的生物可用性,例如hesperidin,fisetin和curcumin.
- 对于封装的多类组,包括蓝安东和可可酸,观察到不一致的结果.
- 化封装证明了在营养药的背景下对黄素的生物可用性有希望的结果.
结论:
- 临床证据支持封装对单个多的好处,但对多混合物不一致.
- 进一步的体内研究对于了解封装多的生物可用性至关重要,特别是在功能性食品中.
- 特定的封装方法,如化,显示了增强多交付的潜力.
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