饮食维生素C与睡眠障碍之间的关联:基于英国生物库的队列研究
Qiuge Zhang1, Xueting Qi1, Zhaoguo Wang2
1Department of Epidemiology and Health Statistics, Public Health College, Qingdao University, Qingdao 266021, China.
Nutrients
|November 9, 2024
概括
饮食中摄入足够的维生素C与睡眠障碍的风险降低有关,包括睡眠呼吸暂停. 更高的维生素C摄入量可能为睡眠健康提供保护性益处.
科学领域:
- 营养科学 营养科学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 睡眠障碍影响全球大约30%的成年人.
- 饮食维生素C与睡眠障碍之间的联系存在有限的纵向研究.
研究的目的:
- 调查饮食维生素C摄入量与睡眠障碍,包括睡眠呼吸暂停和失眠之间的关联.
- 使用受限制的立方斜线模型探索潜在的非线性关系.
主要方法:
- 利用了来自英国生物库的68,221名参与者的数据.
- 通过24小时的饮食回忆问卷评估饮食维生素C摄入量.
- 采用了考克斯回归和受限制的立方支线模型,并进行了分层和灵敏度分析.
主要成果:
- 较高的维生素C摄入量 (Q4: 132.88-191.51 mg/d) 与睡眠障碍的风险降低有显著联系 (HR: 0.78; 95% CI: 0.65-0.94).
- 摄入维生素C显示出与睡眠呼吸暂停 (HR:0.75;95% CI:0.62-0.92) 有着显著的保护性关联.
- 在分层分析 (男性,年龄 ≤ 60) 和灵敏度分析中,保护作用是一致的.
结论:
- 充足的饮食维生素C摄入量可能在预防睡眠障碍方面发挥作用.
- 突出了维生素C作为睡眠健康营养策略的潜力.
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